Epoxidation in Vivo of Hyoscyamine to Scopolamine Does Not Involve a Dehydration Step

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Epoxidation in vivo of hyoscyamine to scopolamine does not involve a dehydration step.

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Determination of Hyoscyamine and Scopolamine in Four Hyoscyamus Species from Iran

The purpose of the present study was to determine the tropane alkaloid content of four Hyoscyamus species from Iran, i.e. H. pusillus L., H. niger L., H. reticulatus L. and H. kurdicus Bornm. Determination of alkaloids was performed by the HPLC method. Samples were extracted with chloroform-methanol-25% ammonium hydroxide 15:5:1 (V/V/V). HPLC separation was performed on Eurospher C18 reversed p...

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Tropane alkaloids such as scopolamine (C17H21NO4), atropine (C17H23NO3) and hyoscyamine (C17H23NO3) are the most important plant secondary metabolites in the pharmaceutical industry due to anticholinergic activity, competition with muscarinic receptors and also treating different human diseases. Scopolamine, hyoscyamine and atropine are the most important tropane alkaloids used as anticoagulant...

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ژورنال

عنوان ژورنال: Plant Physiology

سال: 1987

ISSN: 0032-0889,1532-2548

DOI: 10.1104/pp.84.1.144